Earthquakes come in storms it's been found, one big one starts triggering others like a global domino effect.

It'll be a pandemic that'll have the biggest effect on us, too many people crammed together will let some disease mutate into something almost unstoppable somewhere.
Places like Burma, post disaster, could be a good candidate. Hot, damp, the dead not cleared quickly enough, no way of stopping an outbreak because the medical facilities are destroyed and the regime refusing entry to those who's job it is to help..
